CubaBrief: Remembering when Cuba was on the vanguard of medical research, and today’s dismal reality in the time of COVID-19

Cuba today traffics its doctors abroad for the profit of the dictatorship while Cubans in the island do without.  In the midst of the COVID-19 pandemic there are shortages in Cuba, and a regime that was slow to respond in a constructive manner leading to protests, and public calls for action. Meanwhile PBS is broadcasting Castro propaganda on Cuba’s “vaunted” healthcare system in a program to air Wednesday titled “Cuba’s Cancer Hope”.

The hard reality is that Cuba’s glory days of “cutting-edge” medicine pre-date the Castro regime. I know this first hand because as a child my pediatrician in Little Havana, in a modest office near Flagler Street, was Dr. Agustin Walfredo Castellanos, his patients used to call him “El Chino Castellanos”. He was twice nominated for the Nobel Peace Prize in 1959 and 1960 by Colombia and Ecuador respectively. Dr. Castellanos described “the first practical method of angiocardiography, with which he studied several congenital malformations of the heart. Also, he designed the first automatic angiocardiographic injection device. He also pioneered the method of retrograde injection of contrast material into the aorta which was mainly used to diagnose patent ductus arteriosus.”  Angiocardiography, according to Merriam Webster is “the radiographic visualization of the heart and its blood vessels after injection of a radiopaque substance.

Dr. Castellanos and his colleagues published the first important paper on the clinical applications of intravenous angiocardiography in the Archivos de la Sociedad de Estudios Clinicos in 1937. Cuban medicine prior to 1959 was not just groundbreaking in basic research, but also in public health. Professor James W. McGuire and Laura B. Frankel in their paper published in the Latin American Research Review, “Mortality Decline in Cuba, 1900-1959: Patterns, Comparisons, and Causes” found that “Cuba’s progress relative to other Latin American countries at reducing infant mortality was even greater from 1900 to 1960 than from 1960 to 1995. During the earlier period, Cuba led all Latin American countries for which data are available at raising life expectancy and reducing infant mortality. From 1960 to 1995, by contrast, it came in fourth and fifth respectively.” Numbers don’t lie, although the Castro regime would like to disappear them. 

Thankfully, Glenn Garvin writing at Reason Magazine has burst one of the propaganda bubbles of the Castro dictatorship and its fictitious “lung cancer cure” reporting that “CIMAvax is far from a “cutting-edge” medicine. The truth is that it barely works at all. As Cuba’s Cancer Hope admits in a single throw-away line, “Cuban clinical trials show that it extends life three to five months on average.” The five-year survival rate for its users is about 15 percent, roughly the same as that for patients treated with approved U.S. cancer therapies. American oncologists hoot in frustration at patients who want help getting to Cuba to obtain CIMAvax. Says one, quoted in a recent report by Public Radio International: “Without seeing new stats, it’s not that impressive… . I am not too worried about people not being able to go to Cuba.”

Earlier this month, Castro’s Venezuelan henchman was promoting Cuba’s “interferon” as a cure that saved “around 3,500 lives in China” declaring Cuba in the vanguard, Caribbean National Weekly called it the antidote for COVID-19, and Newsweek was calling it a “wonder drug.” The reality is far more humble. Interferon Alpha-2B Recombinant (IFNrec) was jointly developed with China, but they did not pioneer the discovery of interferon. Interferon research, not surprisingly, was pioneered in Switzerland in the 1950s.  Finally, interferon is not a cure but a possible treatment, with risky side effects that in the late stages of the illness can cause more harm than good. The communist regimes in Cuba and in China are profiting off of the desperation of people around the world caught up in a pandemic that spread out of control because Beijing covered it up for weeks. Sadly, many have fallen for this propaganda.

Screen Shot 2020-03-31 at 2.00.59 PM.png

The Wall Street Journal, March 29, 2020

Cuba Avoids an Honest Coronavirus Policy

Some Cuban teachers, ignoring official pronouncements indicating schools would remain open, closed a school. Ministry of education authorities insisted the students are required to attend classes.

March 29, 2020

Regarding Mary O’Grady’s “Repression in the Time of Coronavirus” (Americas, March 23): It is difficult to imagine a worse situation for Cubans. Last month the regime announced that soap, detergent and disinfectant wouldn’t be available for at least two months.

Despite government efforts, Cubans can no longer be kept ignorant of the outside world due to the internet. As a result there have been protests about the handling of the crisis by figurehead President Miguel Díaz-Canel. After announcing Cuba was closing its borders, thousands of tourists fled.

Some Cuban teachers, ignoring official pronouncements indicating schools would remain open, closed a school. Ministry of Education authorities insisted the students are required to attend classes and should bring “a small piece of soap” to school.

The situation continues to deteriorate. Even the Roman Catholic Church is speaking out. A group of nuns and priests released a document calling on the regime to take urgent measures to slow down the spread of the virus including: “That entry of tourism into the country be stopped, that social isolation be decreed,” educational centers be temporarily suspended and that work be done from home.

They also called on the bishops to suspend religious gatherings including masses. In other countries the church has turned to TV and radio broadcasts for the Eucharist, but in Cuba all stations are owned by the regime. Perhaps the new cardinal and the pope could convince Raúl Castro to allow church access to the electronic media now that churches are closed until the crisis is brought under control.

John Suarez

Executive Director
Center for a Free Cuba
Falls Church, Va.

https://www.wsj.com/articles/cuba-avoids-an-honest-coronavirus-policy-11585506438

Reason, March 27, 2020

Television

No, Cuba Is Not Exactly the Cancer Pioneer Nova Attempts to Present

The myth that this authoritarian island provides better medical treatment just won’t die.

Glenn Garvin | 3.27.2020 2:15 PM

Nova: Cuba’s Cancer Hope.  PBS. Wednesday, April 1, 9 p.m.

I feel moved to poetry by the latest episode of Nova, the PBS science documentary science series. Perhaps you remember the classic lines about the little girl with the little curl in the middle of her forehead: “When she was good/she was very, very good/But when she was bad, she was horrid.”

That’s perfect description of Cuba’s Cancer Hope, which is partly an absorbing exploration of the use of immunology in the treatment of cancer, and partly an embarrassingly puffy ode to the Castro brothers’ totalitarian island. Watching it might trigger your latent schizophrenia; or maybe just induce you to write a pleading letter to TiVo encouraging them to get to work on that long-promised button that allows to automatically skip through communist drivel with a single click. Let me know how it turns out.

As recently as the 1970s, researchers who tried to figure out why the human body’s own immune system didn’t attack cancer cells were derided in medical textbooks as believers in witchcraft. (Seriously: Cuba’s Cancer Hope shows an example, a useful reminder to those who think that Science [cap S is deliberate] speaks with one immutable and eternal voice are quite daft.) The prevailing belief was that T-cells and other warrior elements of the immune system would never attack tumors because they were part of the body itself.

The witches—er, researchers—kept chipping at the cancer-as-self theory until scientists in the United States and Japan won a Nobel prize in 2018 for showing that two proteins that act as brakes on immune cells were being tricked into action by cancer cells. If those proteins could be reined in, the conventional wisdom now goes, the human body itself could be a potent weapon against cancer. Cuba’s Cancer Hope, with sharply illustrative prose and graphics, gives a lucid account of this part of the story.

But when the tale turns to Cuba’s development of a lung-cancer vaccine called CIMAvax that enhances the immunological approach with genetic engineering, the show goes off the rails. Cuba, where the national obsession with cigars has triggered a serious lung cancer problem, began experimenting with the drug in the early 1990s. But it wasn’t until President Obama restored U.S. diplomatic relations with Cuba in 2015 after a 54-year break, making it easier for Americans to visit the island, that CIMAvax attracted much international interest.

On the Internet, it quickly acquired the mythic status once held by laetrile, another supposed cure for cancer suppressed by The Man. Several hundred Americans traveled to Cuba to take CIMAvax, and Cuba’s Cancer Hope is full of testimonials from them—tinged with bitter recriminations against the Trump administration for reviving some of the restrictions on travel to Cuba and forcing them to “break the law” to keep from dying. (Actually, seeking health care in Cuba was never on the list of approved reasons to visit Cuba, and would-be patients can get away with it now the same way they did under Obama: By lying about it to U.S. Customs inspectors, who unless there’s an AK-47 in your suitcase, have no way to check what you were doing there.)

Their stories go unchallenged by Cuba’s Cancer Hope. In fact, the only question the show has about anything is, “How is it possible for a county as poor and isolated as Cuba to come up with cutting-edge medicines like this?” The answer, of course, is the resplendent humanitarianism of Fidel Castro, who raised Cuba from a pestilent sinkhole into a model of public health that rivals anything in the First World. Though the United States gets a little credit for imposing that nasty embargo that forced Cuba to become heroically self-reliant.

A much more accurate answer would be: Cuba did nothing of the kind. It was anything but isolated—its top immunology researchers learned their trade at the University of Texas. Its supposed advances in public health under Castro are imaginary; it ranked near the top of Latin America in life expectancy, infant mortality and a variety of health statistics before Castro took power, a fact that PBS once knew. (As for current health-care data from Cuba, about the only person who believes any of it is Bernie Sanders.)

And most of all, CIMAvax is far from a “cutting-edge” medicine. The truth is that it barely works at all. As Cuba’s Cancer Hope admits in a single throw-away line, “Cuban clinical trials show that it extends life three to five months on average.” The five-year survival rate for its users is about 15 percent, roughly the same as that for patients treated with approved U.S. cancer therapies. American oncologists hoot in frustration at patients who want help getting to Cuba to obtain CIMAvax. Says one, quoted in a recent report by Public Radio International: “Without seeing new stats, it’s not that impressive… . I am not too worried about people not being able to go to Cuba.”

Some American medical authorities think CIMAvax shows promise, and a clinical study of the drug is underway at the Roswell Park Cancer Institute in Buffalo. Perhaps it will someday be proven effective. The same could be said of about 200 other clinical studies of various lung cancer treatments being carried out at the moment, but there’s no sign of Nova doing an episode on “Norway’s Cancer Hope” or “The Mayo Clinic’s Cancer Hope.” Of course, none of them would invite any discussion of the genius of Fidel Castro.

Glenn Garvin is a contributing editor at Reason.

https://reason.com/2020/03/27/no-cuba-is-not-exactly-the-cancer-pioneer-nova-attempts-to-present/